Learn from Your DNA Data
Connect to your raw data from 23andMe, AncestryDNA, MyHeritage, Sequencing.com, TellMeGen, or other raw DNA data to get personalized health, nutrition, and longevity insights.
Tired of advice that doesn’t work for your health, your wellness? Genetic Lifehacks is the top site for genetic insights, with a privacy focus that is unmatched.
It’s easy to get started:
- Step 1: Connect your raw DNA file on the Dashboard (e.g., 23andMe or AncestryDNA raw data format)
- Step 2: Instantly see your genetic reports, along with detailed explanations of ‘why’
- Step 3: View the solutions – the lifehacks – and choose what works for YOU.
More than just a genetic report site:
Genetic Lifehacks explains the background science in-depth, giving you the ability to truly understand what is going on in your body.
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The only major DNA analysis platform that keeps your genetic data 100% private.
- Reports and member features run locally
- No uploading your data, no storage of your private genetic information
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Explore by topic hub:
Latest Genotype Reports:
- Norepinephrine: Focus, stress, genetics, and brain function
Discover how norepinephrine and your genes affect ADHD, ME/CFS, long COVID, POTS, and mood, plus evidence‑based ways to support healthy norepinephrine balance. - Drug-Induced Depletions: Medications and Missing Micronutrients
Common medications can deplete micronutrients, especially when combined with a genetic susceptibility to lower levels of certain vitamins or minerals. If you’re on any prescription drugs, check your genes and consider testing your micronutrient levels. - Dopamine and Digital Addictions: Internet Use, Gaming, and Smartphones
Genetics plays a role in susceptibility to addictive behavior, including internet and smartphone addiction. This article examines the latest fad of dopamine fasting along with genetic variants tied to internet use problems, smartphone usage disorder, and gaming disorders. - Blood-Brain Barrier Genes: SNPs, Leaky BBB Risks & Solutions
Genetic variants can increase susceptibility to blood-brain barrier (BBB) dysfunction. This can increase the risk of Alzheimer’s, ADHD, and mood disorders. - TRPM3: The Ion Channel Behind Pain, Migraines, and ME/CFS
TRPM3 is a calcium ion channel involved in heat sensing, pain transmission, migraines, and immune function. Your TRPM3 gene variants may affect susceptibility to ME/CFS, long Covid, and chronic pain. - Taurine: Healthspan, Mitochondrial Function, and Heart Health
Taking a deep dive into the science behind taurine – from antiaging supplement to heart and digestive health. Genetics plays a role in who may benefit most from supplemental taurine. - Lipoprotein(a): Genetics and Lp(a) Levels
High Lp(a) levels are a big risk factor for sudden heart attacks. Your Lp(a) levels are mainly controlled by your genetic variants. Check to see if you carry genetic variants that increase or decrease Lp(a). - TRPV1 Gene: Receptor for Spicy Foods, Sensing Cold, and CBD Oil
Learn how the TRPV1 gene shapes your reaction to spicy foods, pain, temperature, neuroinflammation and CBD oil, plus see how your genetic variants may affect tolerance and health. - Candida Biology, Pathogenesis, and Genetic Susceptibility
Learn why genetic variants in IL‑17, TLRs, dectin‑1, MBL, FUT2, and STAT1 can make some people much more susceptible to chronic or severe Candida infections.
Recently updated:
Staying up to date with new research is important! Check out these genotype reports that have been updated:
CYP2C19: How Genetic Variants Affect SSRIs, Blood Thinners, and Toxins
CYP2C19 variants can affect how you respond to SSRIs, clopidogrel, diazepam, and PPIs. See what poor or ultra‑rapid metabolizer status may mean for side effects, treatment failure, and toxin metabolism.
CYP2C9: Warfarin Dosing, NSAIDs, THC, and Drug Metabolism
Wonder why warfarin, ibuprofen, THC, or other drugs hit you harder than others? CYP2C9 genetic variants affect drug metabolism, side‑effect risk, and interactions with supplements and other medications.
CYP2C8 Pharmacogenetics: Ibuprofen, NSAID Risk, and Arachidonic Acid
CYP2C8 pharmacogenomics: see how variants in this detox gene change the metabolism of ibuprofen and other drugs, influence bleeding risk, and interact with CYP2C9 and supplements.
CYP2B6: Genetic Variants That Interact with Medications
The CYP2B6 enzyme is part of the body’s first line of defense in detoxifying and breaking down certain and important for metabolizing several medications. Genetic variants of this enzyme can either speed up or slow down its function.
CYP2A6: Breaking down nicotine and other medications
CYP2A6 gene variants shape how fast you break down nicotine and key medications, influencing smoking habits, chemo response, and drug side effects.
CYP1A2 Gene: Fast or Slow Caffeine Metabolizer and More
The CYP1A2 gene breaks down caffeine, melatonin, several major prescription drugs, and interacts with smoking. Learn how your genes influence caffeine metabolism and more.
CYP1A1: Detoxifying Cigarette Smoke and Estrogen
This phase I detoxification gene is important in the breakdown of the hydrocarbons produced in smoke and air pollution. It also affects the metabolism of estrogen.
Should you eat organic? Detoxifying Neonicotinoids
Is buying organic worth the extra cost? Pesticides that are sprayed on conventionally grown foods affect people differently. Some people carry genetic variants that decrease their ability to detoxify specific pesticides, others may be more resilient. This is Part One in a multipart series on pesticide detoxification. (Member’s article)
Multiple Chemical Sensitivity (MCS): Genetics, Causes, and Solutions
Multiple Chemical Sensitivity involves systemic reactions to low-level chemical exposures. Genetic research points to detox enzyme variants and olfactory gene interactions.
Explore by Symptoms, Supplements, Diet, or Pathway:
Symptoms
allergies anemia anxiety arthritis blood pressure brain fog depression dysautonomia eyes fatigue gallbladder hair loss heavy menstrual bleeding high blood pressure intestinal issues itching migraine migraines neuropathy pain peripheral nerves POTS sinus skin small fiber neuropathy stress teeth tinnitus tremor
Supplements
Akkermansia muciniphila alpha-ketogluterate alpha-lipoic acid andrographis apigenin ashwagandha astaxanthin astragalus bacopa berberine biotin calcium calcium d-glucurate carnitine cat's claw CBD cinnamon copper CoQ10 cordyceps creatine curcumin d-mannose dihydromyricetin EGCG fisetin fish oil frankincense ginkgo biloba ginseng glycine glycyrrhizin hesperidin inositol iodine l-arginine l-theanine lion's mane lithium orotate lutein luteolin magnesium manganese melatonin methylene blue methylfolate NAC naringenin nattokinase niacin nicotinamide riboside nigella sativa NMN noopept PEA peppermint probiotics quercetin reishi resveratrol rhodiola riboflavin rosemary rosmarinic acid rutin selenium St. Johns wort sulforaphane taurine thiamine TUDCA vitamin A vitamin B12 vitamin B6 vitamin C vitamin D vitamin E vitamin K zinc
Pathways & Processes
acetylcholine AGEs anandamide arachidonic acid autophagy bile acids bone brown fat cannabinoids catecholamines cholesterol circadian rhythm clots cognitive cold collagen complement system connective tissue dopamine endothelium GABA ghrelin glutathione GSTs gut microbiome HbA1c heat shock proteins histamine hypoxia inborn error of metabolism inflammation intelligence klotho lactose lungs macrophages mannose binding lectin mast cells methylation microbiome mitochondria mTOR muscle neurons non-secretor oxidative stress plant sterols platelets pro-resolving mediators senescence serotonin sirtuins T cells taste receptor triglycerides tryptophan tyramine uric acid vagus nerve vascular
Diseases, Conditions
adenovirus ADHD alpha-1 antitrypsin Alzheimer's asthma autism bipolar cancer celiac cystic fibrosis diabetes dry eyes Ehlers-Danlos epilepsy Epstein-Barr virus fibroids fibromyalgia flu gout heart hemochromatosis IBD infertility lupus lyme macular degeneration ME/CFS miscarriage multiple sclerosis NAFLD nickel obesity osteoporosis osteoporsis Parkinson's PCOS periodontal periodontitis Propionibacterium acnes psoriasis rheumatoid arthritis rosacea seasonal affective disorder Sjogren vaccination vaccines virus
Lifestyle & Diet
acupuncture alcohol anthocyanins aspartame athletics caffeine carbs choline coffee corn syrup cruciferous vegetables fasting fiber fodmaps fructose gluten healthspan iron keto light at night liver longevity organic PFOS polyphenols saturated fat sauna sleep
Genes, Proteins
ACE ADAMS adora2a APOE BDNF BH4 CCR5 COMT Covid GLP-1 GSTM1 GSTP1 hemoglobin HLA HMGB1 homocysteine HPA IGF1 IL-13 IL-17 IL-18 IL-1A IL-1B IL-6 interferon-gamma lp(a) MAO NF-kB nitric oxide NLRP3 telomeres TLR4 TNF-alpha TRPV1 UGTs X chromosome
Hormones
Medications
anesthesia antibiotics aspirin CYP450 drugs metformin nicotine NSAIDs psychodelics rapamycin statins
Toxins
My Story…
Hi! I’m Debbie Moon, founder of Genetic Lifehacks.
When I first had my genetic data sequenced, I was both amazed and frustrated: amazed by all of the genetic research available in academic journals, but frustrated by the disconnected topics and lack of accessibility.
I started Genetic Lifehacks to bridge the gap — to help everyone understand how their genes influence their health, diet, and longevity with practical and useful information based on current research studies.
With my undergraduate degree in engineering as a foundation and a Master’s degree in Biological Sciences from Clemson University (2019), I’ve built Genetic Lifehacks into a platform that has helped over 5 million readers and 19,000+ members to optimize their health through understanding their genetics.
~ Debbie
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