Personalized Genetic Insights from Your DNA Data
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Genetic Lifehacks gives YOU the tools so that you can use your genetic raw data:
- Use your genetic raw data from 23andMe, AncestryDNA, MyHeritage, and more.
- See your genotypes in detailed articles and in summary reports.
- View the solutions; choose what works for YOU.
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‼️ New! Check out the personalized Methylation Cycle Report just for members.
Latest Articles + Genotype Reports:
- Genetics of Mannose-Binding Lectin (MBL) Deficiency
Mannose-binding lectin, also known as mannose-binding protein, is involved in the body’s innate defense against infections. Find out how genetic variants in this system increase your susceptibility to specific pathogens. - IL-2 Genetics and Immune Balance
IL-2 dysregulation affects long COVID, autoimmune diseases, and cancer therapy response. Learn about your IL-2 genetic variants and natural ways to support IL-2. - MMUT Gene Variants and Methylmalonic Acid: Genetics, B12 Status, and Mitochondrial Function
Discover how MMUT gene variants affect your B12 status. High methylmalonic acid (MMA) explains symptoms like fatigue and brain fog—and why adenosylcobalamin may help. - ME/CFS: Myalgic Encephalomyelitis / Chronic Fatigue Syndrome, Genes, Immune Pathways, and Solutions
Learn which immune, mitochondrial, and genetic pathways—NK cells, NLRP3, interferon, complement, TRP channels, and more—may increase susceptibility to ME/CFS. - Thiamine: Genomics, Cellular Energy, and Cognitive Function
Also known as vitamin B1, thiamine is essential for energy production and brain function. Learn how your genes influence your need for thiamine. - Vitamin B5 (Pantothenic Acid): Genetics, Deficiency, and Neurodegenerative Disease
Pantothenic acid (vitamin B5) is essential for coenzyme A synthesis and brain energy. Learn about B5 deficiency, PANK2 mutations, and links to Alzheimer’s. - Borderline Personality Disorder: How Genes, Trauma, and Inflammation Interact
Genetics, epigenetics, and childhood trauma all contribute to BPD. Understand the neurotransmitter disruptions, inflammatory markers, and circadian rhythm issues—with solutions that work. - Artificial Sweeteners: Sucralose, Aspartame, and Genetic Interactions
Health Effects from Artificial Sweeteners; Clinical trials on Sucralose, Aspartame, and Genetic Interactions - Interleukin-15 (IL-15): Immune response, cancer, long Covid, and genetics
Learn how IL-15 influences NK cells and CD8+ T cells in the immune response to pathogens and cancers. Find out how your genetic variants influence IL-15 levels.
Recently updated genetic reports + articles:
Staying up to date is important! Check out these articles that have been updated with new research:
CYP2J2: Arachidonic Acid, Inflammation, and Heart Disease
The CYP2J2 gene is important in the metabolism of arachidonic acid into either pro- or anti-inflammatory lipid signals.
CYP2C9: Genetic Variants and Drug Metabolism
Have you ever wondered why certain medications don’t work well for you? Genetic variants can change how fast or how slow the medication is broken down in your body. Learn how the CYP2C9 variants impact quite a few prescription medications.
CYP2C19 Genetic Variant Impact Medications (SSRIs, Blood Thinners) and Toxins
Several popular drugs, such as omeprazole, esomeprazole, and clopidogrel are metabolized by the CYP2C19 enzyme. There are important genetic variants in the CYP2C19 gene that changes how fast or slowly these drugs are broken down.
CYP2B6: Genetic Variants That Interact with Medications
The CYP2B6 enzyme is part of the body’s first line of defense in detoxifying and breaking down certain and important for metabolizing several medications. Genetic variants of this enzyme can either speed up or slow down its function.
CYP2A6: Breaking down nicotine and other medications
How many cigarettes a day a person smokes – and how hard it is for them to quit – is at least partly dependent on the CYP2A6 gene. This enzyme also metabolizes several important cancer drugs.
CYP1A1: Detoxifying Cigarette Smoke and Estrogen
This phase I detoxification gene is important in the breakdown of the hydrocarbons produced in smoke and air pollution. It also affects the metabolism of estrogen.
CYP17A1: Steroid Hormone Production (Testosterone, Estrogen, and DHEA)
CYP17A1 is important in the production of steroid hormones including testosterone and estrogen. SNPs in CYP17A1 impact hormone levels.
Blood clots, Platelets, and Adenoviruses
Take a look into the role of platelets, their connection to blood clots, and a discussion of the research on adenovirus-vector therapy, thrombocytopenia, and platelet reactions.
Explore by Symptoms, Supplements, Diet, or Pathway:
Symptoms
allergies anemia anxiety arthritis blood pressure brain fog depression dysautonomia eyes fatigue gallbladder hair loss heavy menstrual bleeding high blood pressure intestinal issues itching migraine migraines neuropathy pain peripheral nerves POTS sinus skin small fiber neuropathy stress teeth tinnitus tremor
Supplements
Akkermansia muciniphila alpha-ketogluterate alpha-lipoic acid andrographis apigenin ashwagandha astaxanthin astragalus bacopa berberine biotin calcium calcium d-glucurate carnitine cat's claw CBD cinnamon copper CoQ10 cordyceps creatine curcumin d-mannose dihydromyricetin EGCG fisetin fish oil frankincense ginkgo biloba ginseng glycine glycyrrhizin hesperidin inositol iodine l-arginine l-theanine lion's mane lithium orotate lutein luteolin magnesium manganese melatonin methylene blue methylfolate NAC naringenin nattokinase niacin nicotinamide riboside nigella sativa NMN noopept PEA peppermint probiotics quercetin reishi resveratrol rhodiola riboflavin rosemary rosmarinic acid rutin selenium St. Johns wort sulforaphane taurine thiamine TUDCA vitamin A vitamin B12 vitamin B6 vitamin C vitamin D vitamin E vitamin K zinc
Pathways & Processes
acetylcholine AGEs anandamide arachidonic acid autophagy bile acids bone brown fat cannabinoids catecholamines cholesterol circadian rhythm clots cognitive cold collagen complement system connective tissue dopamine endothelium GABA ghrelin glutathione GSTs gut microbiome HbA1c heat shock proteins histamine hypoxia inborn error of metabolism inflammation intelligence klotho lactose lungs macrophages mannose binding lectin mast cells methylation microbiome mitochondria mTOR muscle neurons non-secretor oxidative stress plant sterols platelets pro-resolving mediators senescence serotonin sirtuins T cells taste receptor triglycerides tryptophan tyramine uric acid vagus nerve vascular
Diseases, Conditions
adenovirus ADHD alpha-1 antitrypsin Alzheimer's asthma autism bipolar cancer celiac cystic fibrosis diabetes dry eyes Ehlers-Danlos epilepsy Epstein-Barr virus fibroids fibromyalgia flu gout heart hemochromatosis IBD infertility lupus lyme macular degeneration ME/CFS miscarriage multiple sclerosis NAFLD nickel obesity osteoporosis osteoporsis Parkinson's PCOS periodontal periodontitis Propionibacterium acnes psoriasis rheumatoid arthritis rosacea seasonal affective disorder Sjogren vaccination vaccines virus
Lifestyle & Diet
acupuncture alcohol anthocyanins aspartame athletics caffeine carbs choline coffee corn syrup cruciferous vegetables fasting fiber fodmaps fructose gluten healthspan iron keto light at night liver longevity organic PFOS polyphenols saturated fat sauna sleep
Genes, Proteins
ACE ADAMS adora2a APOE BDNF BH4 CCR5 COMT Covid GLP-1 GSTM1 GSTP1 hemoglobin HLA HMGB1 homocysteine HPA IGF1 IL-13 IL-17 IL-18 IL-1A IL-1B IL-6 interferon-gamma lp(a) MAO NF-kB nitric oxide NLRP3 telomeres TLR4 TNF-alpha TRPV1 UGTs X chromosome
Hormones
Medications
anesthesia antibiotics aspirin CYP450 drugs metformin nicotine NSAIDs psychodelics rapamycin statins
Toxins
My Story…
Hi! I’m Debbie Moon, founder of Genetic Lifehacks.
When I first had my genetic data sequenced, I was both amazed and frustrated: amazed by all of the genetic research available in academic journals, but frustrated by the disconnected topics and lack of accessibility.
I started Genetic Lifehacks to bridge the gap — to help everyone understand how their genes influence their health, diet, and longevity with practical and useful information based on current research studies.
With my undergraduate degree in engineering as a foundation and a Master’s degree in Biological Sciences from Clemson University (2019), I’ve built Genetic Lifehacks into a platform that has helped over 4 million readers and 17,000 members to optimize their health through understanding their genetics.
~ Debbie