HMB Supplement and Muscle Mass
HMB – hydroxymethylbutyrate – is a supplement that helps to prevent muscle loss in aging and may help with building muscle when working out.
Longevity
Learn how YOUR genes impact longevity and healthspan, and then apply the research-based Lifehacks to optimize your health and prevent the diseases of aging.
Where to start?
- Genetic mutation that protects against Alzheimer’s
- Why melatonin is key to healthy longevity
- Metformin – research and genetic connections
Members: Check out the Longevity Topic Summary Report for a quick overview of all your genetic variants related to longevity.
Aspirin, Colon Cancer Prevention, and Genetics
For some people with specific genetic variants, aspirin may help to prevent colon cancer. Learn more about what the research says and check your genes.
Parkinson’s Disease: Genetics plus Environmental Factors
Parkinson’s disease (PD) is not yet fully understood. Researchers think that it is caused by a combo of genetics and environmental factors. Learn more about this disease and the factors that lead to susceptibility.
Alzheimer’s Gene: Find your APOE type from your genetic raw data
The APOE gene variants are linked with the risk of Alzheimer’s disease. Find out whether you carry the APOE risk type for Alzheimer’s – and learn what research shows about supplements and lifestyle changes to prevent this disease.
Nicotinamide Riboside and NMN: Boosting NAD+ in Aging
Explore the research about how nicotinamide riboside (NR) and NMN are being used to reverse aging. Learn about how your genes naturally affect your NAD+ levels and how this interacts with the aging process.
Taurine: Research on Healthspan and Supplements
Taking a deep dive into the science behind taurine – from antiaging supplement to heart and digestive health. Genetics plays a role in who may benefit most from supplemental taurine.
APOE and COMT: Cognitive performance in aging
Your APOE and COMT genotypes together may impact memory and cognitive function in older age.
Alpha-Ketoglutarate: A Key to Healthspan and Fighting Age-Related Diseases
Supplementing with Alpha-ketoglutarate (αKG) might be beneficial for longevity since it plays a role in energy production and inflammation reduction.
Klotho VS Reduces Alzheimer’s Risk for APOE E4 Carriers
The Klotho protein is involved in many of the diseases of aging. Learn more about this gene and find out how your Klotho variants may impact healthy aging.
SIRT3, Aging, and Mitochondrial Function
How we age is just as important as how long we live. Examine how sirtuins play a part in the aging process by how they regulate our cellular health.
BPIFB4 Gene: Linked to Longevity and Heart Health
Discover the impact of the BPIFB4 gene on longevity and immunity, and find out if you have the longevity variant in your genotype report.
Skin Aging: Using genomics to solve wrinkles and age spots
Some people age naturally with beautiful-looking skin. Others slather on creams and odd gunk in a futile battle to chase away wrinkles and age spots. What is the difference? Genetics and environmental factors, of course.
Guide: Saving Money on Supplements
Five quick examples of how you could use your genetic data to dial in the supplements worth trying and which ones to skip for now.
Longevity Genes: Hacking healthspan using genomics
Several genes have been identified as longevity genes, linked to an increase in lifespan. Most importantly, these particular genetic variants show links to a longer ‘healthspan’. Check your genetic data to see if you carry the FOXO3A and IGF1R variants associated with healthy longevity.
Rapamycin, mTOR, and Your Genes
Rapamycin is an antibiotic used as an immunosuppressant, an anti-cancer agent, and to prevent blocked arteries. Rapamycin is now the focus of longevity and healthspan-extending research by inhibiting mTOR.
Serotonin 2A receptor: Psychedelic response and Alzheimer’s disease
Learn how new research on brain aging and dementia connects the serotonin 2A receptor with psychedelics, brain aging, and Alzheimer’s.
Genetic Mutations that Protect Against Alzheimer’s Disease
Just like there are genetic variants that increase the risk of Alzheimer’s, there are also variants that protect against this disease. Check your genetic data to get a better picture of your risk factors. (Member’s article)
Intermittent Fasting: Benefits from changing Gene Expression
The intermittent fasting concept has gained traction in health circles. Learn more about the importance of when you eat and its effects on gene expression.
TREM2 and Alzheimer’s Disease Risk
The TREM2 gene is important in how the brain’s immune system functions. Learn how variants in this gene impact the risk for Alzheimer’s disease.
SIRTfoods diet: Sirtuins and turning on your skinny genes
The SIRTfood diet, made popular by Adele’s recent weight loss, theoretically works by affecting your sirtuin gene expression. Learn about your SIRT genes and your genetic variants.
Age-Related Macular Degeneration Genes
Age-related macular degeneration (AMD) is the most common cause of blindness in the elderly. You will find supplements specifically promoted for preventing AMD. This article explains age-related macular degeneration, delves into the genetic risks, and then explains which supplements are likely to be protective and which may do more harm than good.
Nitric Oxide Synthase (NOS3): Heart health, blood pressure, and healthy aging
Nitric Oxide Synthase is an important signaling molecule in the endothelium of our blood vessels. It has roles in the regulation of blood pressure, cardiovascular disease, brain health, and more. Genetic variants in nitric oxide genes are important for a healthy heart. Find out how your genes could play a part in the interactions with cardiovascular disease risk and blood pressure.
Melatonin: Key to Health and Longevity
More than just a sleep hormone, melatonin is at the heart of many health topics. Your genetic variants play a big role in the production of melatonin. Learn how your lifestyle and diet interact with your melatonin-related genes.
Building Up Iron: Hemochromatosis mutations
A couple of common mutations can cause you to build up iron, leading to iron overload or hemochromatosis. It is one genetic disease where knowledge is really powerful – you can completely prevent hemochromatosis through blood donations.
Longevity Summary Report
Utilize our Longevity Topic Summary Reports with your 23andMe or AncestryDNA genetic data to see which articles may be most relevant to you. These summaries are attempting to distill the complex information down into just a few words. Please see the linked articles for details and complete references. (Member’s article)