von Willebrand factor

Von Willebrand Factor Deficiency

von Willebrand disease is a bleeding disorder in which blood doesn’t clot properly. Discover how genetic mutations cause the von Willebrand factor not to perform as it should.

Aldosterone

Hypertension Risk Factor: CYP11B2 Variant

Hypertension risk can be modifiable in terms of diet and exercise however genetics can play a part in risk. Learn more about how the CYP11B2 variant can increase the risk of hypertension.

genes related to cholesterol 23andMe AncestryDNA

LDL Cholesterol Genes

Your genes combine with your diet to influence your LDL cholesterol level. Learn more about why LDL cholesterol levels may matter in heart disease and find out how your genes are important here.

Lipoprotein a: How to check your genetic data

High Lp(a) levels are a big risk factor for sudden heart attacks. Your Lp(a) levels are mainly controlled by your genetic variants. Check to see if you carry genetic variants that increase or decrease Lp(a).

Will Aspirin Prevent Heart Disease?

While large population studies show the benefits of aspirin, research shows that these heart-health benefits are dependent on your genes. Find out more and check your genetic raw data.

Nitric Oxide Synthase: Heart health, blood pressure, and aging

Nitric Oxide Synthase is an important signaling molecule in the endothelium of our blood vessels. It has roles in the regulation of blood pressure, cardiovascular disease, brain health, and more. Genetic variants in nitric oxide genes are important for a healthy heart. Find out how your genes could play a part in the interactions with cardiovascular disease risk and blood pressure.

blood clots

Elevated Fibrinogen: Risk factor for blood clots

Fibrinogen is a protein that is essential for creating blood clots when you get a wound. But higher levels of fibrinogen are a major risk factor for heart disease and DVT. Learn how your genes impact your fibrinogen level.

7 genetic variants that increase your risk of blood clots

Some people are unique in their ability to form clots more easily. This article covers six different genes and the seven genetic variants that increase the risk of blood clots. It is a timely topic because blood clots seem to be a severe complication for people with COVID-19.

The genetics of high triglycerides

High triglycerides are linked with an increased risk of cardiovascular disease. Both genetics and diet combine to elevate triglyceride levels. Learn how your genes interact with what you eat to lower your triglycerides.

Building Up Iron: Hemochromatosis mutations

A couple of common mutations can cause you to build up iron, leading to iron overload or hemochromatosis. It is one genetic disease where knowledge is really powerful – you can completely prevent hemochromatosis through blood donations.

Heart Health Topic Summary

Utilize our Heart Health Topic Summary Reports with your 23andMe or AncestryDNA genetic data to see which articles may be most relevant to you. These summaries are attempting to distill the complex information down into just a few words. Please see the linked articles for details and complete references. (Member’s article)

Plant Sterols for Lowering Cholesterol? Depends on Your Genes

Plant sterols are known as a ‘heart-healthy’ way to lower cholesterol. But, it turns out that they may only lower cholesterol only in people with certain genetic variants. Check your genes to see if adding plant sterols is worthwhile for you.

Advanced Glycation End Products

One cause of many of the diseases of aging is the buildup of advanced glycation end products (AGEs). Your genes interact with your diet – and cooking methods – in the build-up of AGEs. Learn whether this is something that is important for you to focus on. (Member’s article)

High blood pressure due to AGTR1 gene variants

There are several causes of high blood pressure. Genetic variants in the AGTR1 gene are strongly linked with blood pressure and there are specific lifestyle changes that should work to change your blood pressure if you carry the variants.

Saturated Fat and Your Genes

There has been a decades-long debate about which type of fat is best: saturated fat vs polyunsaturated fat. It may depend on your genes as to which answer is right for you. Learn more about this debate and find out how your genes play a part.

ITGB3: Heart attack risk – with a positive tradeoff

The PIA2 variant of the ITGB3 gene is linked to an increased risk of blood clots including stroke, heart attack, and DVT. But this variant also comes with a positive trade-off. Learn more with your genetic raw data.

C-Reactive Protein Gene: Marker of Inflammation

Chronic inflammation is the driver of many common diseases such as heart attacks, diabetes, obesity, and autoimmune diseases. C-Reactive Protein is a marker of inflammation. Genetic variants can increase or decrease CRP levels.

Prothrombin: Blood Clot Risk

Genetic variants in the prothrombin gene increase the risk of blood clots (DVTs). Learn if you carry this risk factor for miscarriage, blood clots, and stroke.

Factor V Leiden Gene

The factor V Leiden genetic mutation significantly increases the lifetime risk of blood clots. Check your genetic data to see if you carry this mutation – and then learn to recognize the symptoms of blood clots.