Neuropilins: Healthy blood vessels, lymphedema, Covid brain
Neuropilins act as receptors and are found on the surface of cells. Learn about its many roles body, such as in the immune, vascular and nervous systems.
Heart Health
Heart disease is the number one cause of death, making heart health a priority for everyone!
Heart disease, though, is a catch-all term that applies to many different conditions. These articles will show you where your genetic susceptibility lies – and what to do about it.
Member’s: Check out the Heart Health Topic Summary Report for a quick overview of all your genetic variants related to heart health.
ADRA1A Receptors: Blood vessel reactions under stress
We have many systems in place to control blood pressure and heart rate. The ADRA1A receptors are part of this system. Discover how variants can influence blood vessel stress response and how others are connected to cognitive changes.
7 genetic variants that increase your risk of blood clots
Some people are unique in their ability to form clots more easily. This article covers six different genes and the seven genetic variants that increase the risk of blood clots. It is a timely topic because blood clots seem to be a severe complication for people with COVID-19.
Spike Protein, Mast Cells, Histamine, and Heart Rhythms
Do you know of someone with unexplained heart palpitations, spiking blood pressure, dizziness, and tinnitus? Discover how research is linking these symptoms to histamine, mast cells, and the spike protein.
Lipoprotein a: How to check your genetic data
High Lp(a) levels are a big risk factor for sudden heart attacks. Your Lp(a) levels are mainly controlled by your genetic variants. Check to see if you carry genetic variants that increase or decrease Lp(a).
Nattokinase and Lumbrokinase: Natural supplements for clots
Two natural fibrinolytics to reduce clotting are nattokinase and lumbrokinase. Learn more about these options based upon the newest research and clinical trials.
Von Willebrand Factor Deficiency
von Willebrand disease is a bleeding disorder in which blood doesn’t clot properly. Discover how genetic mutations cause the von Willebrand factor not to perform as it should.
What is YOUR risk of heart disease?
Coronary artery disease (CAD) is heritable. Understanding your genes and a ‘heart healthy’ lifestyle can prevent heart attacks and death.
Boosting NAD+ to Reverse Aging? Overview of NR and NMN
Explore the research about how nicotinamide riboside (NR) and NMN are being used to reverse aging. Learn about how your genes naturally affect your NAD+ levels and how this interacts with the aging process.
LDL Cholesterol Genes
Your genes combine with your diet to influence your LDL cholesterol level. Learn more about why LDL cholesterol levels may matter in heart disease and find out how your genes are important here.
Elevated Fibrinogen: Risk factor for blood clots
Fibrinogen is a protein that is essential for creating blood clots when you get a wound. But higher levels of fibrinogen are a major risk factor for heart disease and DVT. Learn how your genes impact your fibrinogen level.
ADAMTS13 and VWF Genetic Variants: blood clots and thrombocytopenia
Genetic Variants involving the ADAMTS13 gene and VWF (von Willebrand Factor) can increase the risk of blood clots and thrombocytopenia.
Will Aspirin Prevent Heart Disease for You?
While large population studies show the benefits of aspirin, research shows that these heart-health benefits are dependent on your genes. Find out more and check your genetic raw data.
PCSK9 Gene: Understanding the variants that cause high or low LDL cholesterol
There are several important variants in the PCSK9 gene. Some variants cause lower LDL-cholesterol and decrease the risk of heart disease by 2-fold. Other variants increase LDL-c and increase the risk of heart disease.
Nitric Oxide Synthase: Heart health, blood pressure, and aging
Nitric Oxide Synthase is an important signaling molecule in the endothelium of our blood vessels. It has roles in the regulation of blood pressure, cardiovascular disease, brain health, and more. Genetic variants in nitric oxide genes are important for a healthy heart. Find out how your genes could play a part in the interactions with cardiovascular disease risk and blood pressure.
Hypertension Risk Factor: CYP11B2 Variant
Hypertension risk can be modifiable in terms of diet and exercise however genetics can play a part in risk. Learn more about how the CYP11B2 variant can increase the risk of hypertension.
The genetics of high triglycerides
High triglycerides are linked with an increased risk of cardiovascular disease. Both genetics and diet combine to elevate triglyceride levels. Learn how your genes interact with what you eat to lower your triglycerides.
Building Up Iron: Hemochromatosis mutations
A couple of common mutations can cause you to build up iron, leading to iron overload or hemochromatosis. It is one genetic disease where knowledge is really powerful – you can completely prevent hemochromatosis through blood donations.
Plant Sterols for Lowering Cholesterol? Depends on Your Genes
Plant sterols are known as a ‘heart-healthy’ way to lower cholesterol. But, it turns out that they may only lower cholesterol only in people with certain genetic variants. Check your genes to see if adding plant sterols is worthwhile for you.
Advanced Glycation End Products
One cause of many of the diseases of aging is the buildup of advanced glycation end products (AGEs). Your genes interact with your diet – and cooking methods – in the build-up of AGEs. Learn whether this is something that is important for you to focus on. (Member’s article)
BMAL1: Core circadian gene with links to heart disease, cancer, and diabetes
A core circadian rhythm gene, BMAL1, influences heart disease risk, diabetes, and cancer. Check your genes and learn how to mitigate the risk.
High blood pressure due to AGTR1 gene variants
There are several causes of high blood pressure. Genetic variants in the AGTR1 gene are strongly linked with blood pressure and there are specific lifestyle changes that should work to change your blood pressure if you carry the variants.
Will statins give you muscle pain?
Statins are one of the most prescribed medications in the world. One side effect of statins is myopathy, or muscle pain and weakness. Your genetic variants are significant in whether you are likely to have side effects from statins.
ITGB3: the PIA1/A2 variant and clotting
The PIA2 variant of the ITGB3 gene is linked to an increased risk of blood clots including stroke, heart attack, and DVT. But this variant also comes with a positive trade-off. Learn more with your genetic raw data.
C-Reactive Protein (CRP): Marker of Inflammation
Chronic inflammation is the driver of many common diseases such as heart attacks, diabetes, obesity, and autoimmune diseases. C-Reactive Protein is a marker of inflammation. Genetic variants can increase or decrease CRP levels.
Prothrombin: Blood Clot Risk
Genetic variants in the prothrombin gene increase the risk of blood clots (DVTs). Learn if you carry this risk factor for miscarriage, blood clots, and stroke.