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Back Pain: Genetics, Root Causes, and Solutions

Back Pain: Genetics, Root Causes, and Solutions

For some people, back pain is a daily occurrence that drastically affects their quality of life. For others, it may be an intermittent nagging problem, often without rhyme or reason. Your genes play a role in whether disc degeneration gives you back pain.

IL-13 Asthma risk, natural inhibitors of IL-13, IL-13 genetic variants

IL-13: Elevating Th2 Immune Response and Asthma risk

Interleukin-13 (IL-13) is a signaling molecule important in the immune response. Excessive IL-13 can tip you toward a Th2-dominant immune response, and variants increase the risk of allergies and asthma.

HMGB1: From Nuclear Organizer to Inflammatory Alarmin

HMGB1 gene: inflammatory response protein important in sepsis and COVID-19

The HMGB1 protein has a unique role in activating the inflammatory response pathways. Increased HMGB1 levels will call up the troops for a big response to an infection. Discover how genetic variants of this protein vary the risk of cancer, inflammation, and sepsis to name a few.

Increased Inflammation and IL-17A Genetic Variants

Increased Inflammation and IL-17A Genetic Variants

Some people have a more sensitive immune system and are more prone to inflammatory reactions. We need a balance in the body between fighting off pathogens and not having too much of an inflammatory response. Learn more about what triggers inflammation and how your genes play a part.