LDL Cholesterol Genes

Your genes combine with your diet to influence your LDL cholesterol level. Learn more about why LDL cholesterol levels may matter in heart disease and find out how your genes are important here.

GLP-1: Appetite, Insulin, and Genetics

GLP-1, a small peptide, tells your pancreas to release insulin after a meal and signals to your brain to stop eating. If you are someone who struggles with appetite, weight, or with diabetes, the GLP-1 hormone may be at the heart of your issues.

FTO is more than just an obesity gene

FTO and m6A methylation: From COVID to Cancer to Obesity

The initial research on the FTO gene was all about how it relates to increased BMI and increased fat cell creation. More recently, researchers discovered that FTO is an m6A eraser that removes methyl groups from mRNA. This discovery has opened up huge avenues of research on topics from cancer to immune response to heart disease.

Genetic Weight Loss Report

This DIY genetics report shows you how your genetic raw data for weight-related genes are linked to your weight. We are all different, and a one-size-fits-all approach to weight loss does not work for everyone.

Decrease diabetes risk with coffee

Does coffee increase or decrease your risk of prediabetes? Learn more about coffee consumption and your genetic risk. (Member’s article)

PCOS: Genetics and Root Causes

Polycystic ovarian syndrome (PCOS) is an endocrine disorder causing an increase in androgen hormone production in women. It also increases the risk of infertility. PCOS affects 5 -10% of premenopausal women, and genetics plays a large role in whether you have PCOS.

An Adenovirus Causes Weight Gain

There have been several interesting studies linking obesity to a viral infection, specifically an adenovirus. Learn more about this virus and its association with obesity.

Diabetes: Genetic Risk Report

We often talk about diabetes as though it is one disease, but diabetes can have several different causes or pathways that are impacting glucose regulation. Tailoring your diabetes prevention (or reversal) efforts to fit your genetic susceptibility may be more effective. Use your genetic raw data to learn more about diabetes and your genetic risk.

SCD1: A lynchpin of metabolism

The SCD1 enzyme converts saturated fatty acids to unsaturated fats. Learn how your genes impact this enzyme, and how this relates to weight loss.

Nitric Oxide Synthase: Heart health, blood pressure, and aging

Nitric Oxide Synthase is an important signaling molecule in the endothelium of our blood vessels. It has roles in the regulation of blood pressure, cardiovascular disease, brain health, and more. Genetic variants in nitric oxide genes are important for a healthy heart. Find out how your genes could play a part in the interactions with cardiovascular disease risk and blood pressure.

Carbohydrate metabolism: Genetics, Insulin, and Carbs

Genetic variations play a role in how people react to carbohydrates in the diet. Learn about a few genes that affect insulin or glucose levels based on carbohydrate consumption. Use your genetic raw data and discover how your body handles carbohydrates.

The genetics of high triglycerides

High triglycerides are linked with an increased risk of cardiovascular disease. Both genetics and diet combine to elevate triglyceride levels. Learn how your genes interact with what you eat to lower your triglycerides.

Genetic Links to High Uric Acid and Gout

High uric acid levels can cause the pain and inflammation of gout. Find out how your genetic variants influence your uric acid levels and gout risk. (Member’s article)

A Sweet Tooth Without Weight Gain: FGF21 Gene

The FGF21 gene codes for a hormone that is created in the liver and is important for appetite regulation. One variant is linked to increasing carbohydrate consumption – but without an increase in weight gain or diabetes. (Member’s article)

SCADD

Short-chain Acyl-CoA Dehydrogenase Deficiency

If you have tried fasting or perhaps a ketogenic diet and felt horrible, there could be a genetic reason. You might carry a genetic mutation that causes SCADD (short-chain acyl-CoA dehydrogenase deficiency).

High blood pressure due to AGTR1 gene variants

There are several causes of high blood pressure. Genetic variants in the AGTR1 gene are strongly linked with blood pressure and there are specific lifestyle changes that should work to change your blood pressure if you carry the variants.

Saturated Fat and Your Genes

There has been a decades-long debate about which type of fat is best: saturated fat vs polyunsaturated fat. It may depend on your genes as to which answer is right for you. Learn more about this debate and find out how your genes play a part.

Genetics and Type 2 Diabetes

Not all type 2 diabetes risk is from what you eat… Genetics plays a big role in diabetes. Learn more about your genetic susceptibility.

Medium chain acyl-CoA dehydrogenase deficiency

Medium-chain acyl-CoA dehydrogenase (MCAD) deficiency is an “inborn error of metabolism” which impairs the body’s ability to break down medium-chain fatty acids for fuel. Learn more about this metabolic disorder.