Understanding how your genes impact your neurotransmitters can help you to better optimize mood and cognitive function.
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GABA (gamma-Aminobuyteric acid) is a neurotransmitter that acts to block or inhibit a neuron from firing. It is an essential way that the brain regulates impulses, and low GABA levels are linked with several conditions, including anxiety and PTSD.
Explore brain fog in detail, looking at the physiological causes, genetic susceptibility, and personalized solutions.
Tryptophan is an amino acid that the body uses to make serotonin and melatonin. Genetic variants can impact the amount of tryptophan that is used for serotonin. This can influence mood, sleep, neurotransmitters, and immune response.
Depression can have multiple physiological causes. This article ties together 9 separate articles on depression to simply your genetic search.
This article covers genetic variants related to anxiety disorders. Genetic variants combine with environmental factors (nutrition, sleep, relationships, etc) when it comes to anxiety. There is not a single “anxiety gene”. Instead, there are many genes that can be involved – and many genetic pathways to target for solutions.
Your genes play a role in your susceptibility to migraines. Find out what is going on when you have a migraine and solutions that fit your genes.
Cortisol is a hormone produced by the adrenal glands in times of stress, and it also plays many roles in your normal bodily functions. It is a multi-purpose hormone that needs to be in the right amount (not too high, not too low) and at the right time. Your genes play a big role in how likely you are to have problems with cortisol.
Nootropics are supplements used to boost cognition and memory. Learn how the substance works and the genes connected to the mechanism of action.
For some people, low-dose, supplemental lithium orotate is a game changer when combined with vitamin B12. But other people may have little to no response. The difference may be in your genes.
Can you be born a psychopath? Are there genes linked to psychopathy? Discover how your genes don’t predestine you to become a psychopath.
Serotonin is a neurotransmitter that is important in depression, sleep, and many other aspects of health. Learn how your genetic variants in the serotonin receptor genes impact their function.
An examination of the current research for the ‘God gene’, explaining what it does and its importance in Parkinson’s disease.
How does mitochondrial dysfunction relate to major depressive disorder? Learn about the causes of mitochondrial dysfunction as well as genetic variants that link the risk of depression to the mitochondria.
We are all genetically unique, and a common genetic variant in the MTHFR gene causes some people to be more susceptible to having low folate levels. This article explains the research linking MTHFR variants, folate, and depression — and gives you information on how diet or supplements may help.
Some supplements interact with COMT variants to impact the rate at which neurotransmitters are broken down. Check your COMT genotype and discover how this may affect your reaction to different supplements or combinations of supplements.
Learn how new research on brain aging and dementia connects the serotonin 2A receptor with psychedelics, brain aging, and Alzheimer’s.
Discover why inflammation causes depression and how your genetic variants in inflammatory genes may play a role in depression or anxiety.
Why do some people get such great benefits from CBD while others notice nothing? Your genes play a role in how your body responds to CBD.
The genetic variants in the ANK3 gene impact the risk of psychiatric disorders that include bipolar disorder and autism spectrum disorders, and heart arrhythmia. Discover how ANK3 impacts neuronal formation and transmission and how this ties into an increased risk of psychiatric disorders.
For some people, circadian disruption can be chronic – and at the heart of depression or mood disorders. Genetic variants play a role in this susceptibility. Fortunately, there are solutions that may help.
Modafinil is a prescription medication (in the US) for decreasing daytime drowsiness in narcolepsy patients. Off-label, it is a popular …
Seasonal Affective Disorder (SAD) is characterized by recurrent depression with a change in the season usually in fall/winter for most. Scientists think this is possibly due to an aberrant response to light – either not enough brightness to the sunlight or not enough hours of light. Your genes play a big role in this responsiveness to light.
Genetics plays a role in susceptibility to addictive behavior, including internet and smartphone addiction. This article examines the latest fad of dopamine fasting along with genetic variants tied to internet use problems, smartphone usage disorder, and gaming disorders.
Wondering why your neurotransmitters are out of balance? It could be due to your COMT genetic variants. The COMT gene codes for the enzyme catechol-O-methyltransferase which breaks down (metabolizes) the neurotransmitters dopamine, epinephrine, and norepinephrine.
Discover how genetic variants influence your susceptibility to substance abuse, and how the variants impact your body’s reaction to cannabis. (Member’s article)
New research shows that depression and bipolar disorder are linked to changes or disruption in circadian genes. Some people carry genetic variants in the circadian genes that make them more susceptible to circadian disruption.