Join Here   |   Log In
GABA neurotransmitter, recycling and synthesis, genetic variants affecting GABA, ways to naturally increase GABA

GABA: Genetics, Anxiety, and Immune Response

GABA (gamma-Aminobuyteric acid) is a neurotransmitter that acts to block or inhibit a neuron from firing. It is an essential way that the brain regulates impulses, and low GABA levels are linked with several conditions, including anxiety and PTSD.

Genetic Causes of Depression, 9 Genetic pathways that cause depression, Circadian Rhythm, BDNF, Serotonin genes

Root Cause(s) of Depression

Depression can have multiple physiological causes. This article ties together 9 separate articles on depression to simply your genetic search.

Psychopathy Genetics, epigenetics, environmental factors involved in psychopathy

Psychopaths: Born not made?

Can you be born a psychopath? Are there genes linked to psychopathy? Discover how your genes don’t predestine you to become a psychopath.

Supplements to Boost BDNF

Best Supplements to Boost BDNF

Is it smart to boost your BDNF levels? Discover more by digging into the research studies that show when, how, and why it is important to focus on BDNF.

How Genetics Affects Serotonin, serotonin transport and receptors

Serotonin: How Your Genes Affect this Neurotransmitter

Serotonin is a neurotransmitter that is important in depression, sleep, and many other aspects of health. Learn how your genetic variants in the serotonin receptor genes impact their function.

Depression, Genetics, and Mitochondrial Function

Depression, Genetics, and Mitochondrial Function

How does mitochondrial dysfunction relate to major depressive disorder? Learn about the causes of mitochondrial dysfunction as well as genetic variants that link the risk of depression to the mitochondria.

MTHFR variants and depression and anxiety

MTHFR, Depression, Anxiety, Symptoms and Treatment

We are all genetically unique, and a common genetic variant in the MTHFR gene causes some people to be more susceptible to having low folate levels. This article explains the research linking MTHFR variants, folate, and depression — and gives you information on how diet or supplements may help.

CBD Oil: Will it work for you?

Why do some people get such great benefits from CBD while others notice nothing? Your genes play a role in how your body responds to CBD.

ANK3: Bipolar Disorder and Brain Development

ANK3: Bipolar Disorder and Brain Development

The genetic variants in the ANK3 gene impact the risk of psychiatric disorders that include bipolar disorder and autism spectrum disorders, and heart arrhythmia. Discover how ANK3 impacts neuronal formation and transmission and how this ties into an increased risk of psychiatric disorders.

Circadian rhythm disruption as a root cause of depression

For some people, circadian disruption can be chronic – and at the heart of depression or mood disorders. Genetic variants play a role in this susceptibility. Fortunately, there are solutions that may help. ​

Genetics and Seasonal Affective Disorder

Genetics and Seasonal Affective Disorder

Seasonal Affective Disorder (SAD) is characterized by recurrent depression with a change in the season usually in fall/winter for most. Scientists think this is possibly due to an aberrant response to light – either not enough brightness to the sunlight or not enough hours of light. Your genes play a big role in this responsiveness to light.

Dopamine Fasting: Addicted to the internet?

Genetics plays a role in susceptibility to addictive behavior, including internet and smartphone addiction. This article examines the latest fad of dopamine fasting along with genetic variants tied to internet use problems, smartphone usage disorder, and gaming disorders.

COMT Graphical Abstract, Slow COMT effects, Slow COMT

COMT Gene: Neurotransmitter Levels, Estrogen Metabolism, and SNPs

Wondering why your neurotransmitters are out of balance? It could be due to your COMT genetic variants. The COMT gene codes for the enzyme catechol-O-methyltransferase which breaks down (metabolizes) the neurotransmitters dopamine, epinephrine, and norepinephrine.

Response to Cannabis (CNR1 gene)

Discover how genetic variants influence your susceptibility to substance abuse, and how the variants impact your body’s reaction to cannabis. (Member’s article)

Bipolar Disorder, Depression, and Circadian Clock Genes

Bipolar Disorder, Depression, and Circadian Clock Genes

New research shows that depression and bipolar disorder are linked to changes or disruption in circadian genes. Some people carry genetic variants in the circadian genes that make them more susceptible to circadian disruption.

BDNF Val66Met, The Interaction Between BDNF and Serotonin

The Interaction Between BDNF and Serotonin

Genetic variants in the BDNF and serotonin receptor genes combine to increase the risk of depression and anxiety. Learn more about BDNF and how these variants interact — and check your genetic data to see how this applies to you.

Childhood trauma

Resilience: Genetic Variants Involved in Surviving Childhood Trauma

Exposure to childhood trauma, such as exposure to abuse, violence, or repeated stress, can have a long-lasting effect. Genetic differences in the CRHR1 gene are linked to elevated cortisol levels in adults who were exposed to trauma in childhood.

BDNF: Cognition, Stress Resilience, Introversion, and Mood

BDNF: Cognition, Stress Resilience, Introversion, and Mood

Low levels of BDNF (Brain-derived neurotrophic factor) are linked to introversion, stress resilience, cognition, and depression levels. Discover ways to increase your BDNF levels and mitigate the problems associated with the BDNF gene variants. (Member’s article)

Circadian Rhythm Disruption and Mood Disorders

Circadian Rhythm Genes: Mood Disorders

Circadian rhythm disruption can drive mood disorders. Learn more about the genes involved and the ways to normalize your circadian rhythm.