Response to Cannabis (CNR1 gene)

Discover how genetic variants influence your susceptibility to substance abuse, and how the variants impact your body’s reaction to cannabis. (Member’s article)

mood disorders

Bipolar Disorder, Depression, and Circadian Clock Genes

New research shows that depression and bipolar disorder are linked to changes or disruption in circadian genes. Some people carry genetic variants in the circadian genes that make them more susceptible to circadian disruption.

The Interaction Between BDNF and Serotonin

Genetic variants in the BDNF and serotonin receptor genes combine to increase the risk of depression and anxiety. Learn more about BDNF and how these variants interact — and check your genetic data to see how this applies to you.

Dopamine Receptor Genes

Dopamine is a powerful player in our cognitive function – impacting mood, movement, and motivation. Genetic variants in the dopamine receptors influence addiction, ADHD, neurological diseases, depression, psychosis, and aggression.

Opioid Receptors: Turning Off Pain

Genetic variants in the ORPM1 gene impact both the amount of pain someone experiences and their response to opioid drugs. These variants are also important in susceptibility to opiate addiction. (Member’s article)

BDNF variants

BDNF: introversion, stress resilience, cognition, and depression

Low levels of BDNF (Brain-derived neurotrophic factor) are linked to introversion, stress resilience, cognition, and depression levels. Discover ways to increase your BDNF levels and mitigate the problems associated with the BDNF gene variants. (Member’s article)

Hacking BDNF for weight loss

Brain-derived neurotrophic factor (BDNF) is a fascinating growth hormone that performs many functions in our brain. Its involvement helps to support neurons and neuronal growth. In addition, it plays a role in long-term memory — and it also is important in obesity.