The hypoxia-inducible factor-1 alpha (HIF1A) gene codes for a transcription factor, that responds to the amount of oxygen available to the cell. This is important in cancer prevention, and several HIF1A genetic variants alter the susceptibility to several types of cancer.
Genetics plays a big role in how well your body breaks down histamine. You can use your genetic data to figure out if your genes are part of the reason why you have histamine intolerance.
Are you dealing with dry eyes and dry mouth? Sjögren’s syndrome is an autoimmune disorder that affects moisture-producing glands. Discover the underlying causes of Sjögren’s syndrome and the genetic variants that increase susceptibility.
The intermittent fasting concept has gained traction in health circles. Learn more about the importance of when you eat and its effects on gene expression.
The CTLA4 gene codes for a protein that is important in the immune system. It acts as a checkpoint that can downregulate your immune system response. Genetic variants in the CTLA4 gene can increase your risk for several different autoimmune diseases. (Member’s article)
How we age is just as important as how long we live. Examine how sirtuins play a part in the aging process by how they regulate our cellular health.
We have many systems in place to control blood pressure and heart rate. The ADRA1A receptors are part of this system. Discover how variants can influence blood vessel stress response and how others are connected to cognitive changes.
Learn why zinc is important for your immune system and so much more. Find out how your genes impact your need for zinc and discover ways of boosting your zinc status.
MS susceptibility is linked to both genetic causes and environmental factors. Learn how those two combine – and possible solutions.
Explore the complexities of PCOS, including symptoms, hormonal dysregulation, and the role of genetics. Learn how to target individual pathways.
The SIRTfood diet, made popular by Adele’s recent weight loss, theoretically works by affecting your sirtuin gene expression. Learn about your SIRT genes and your genetic variants.
The CCR5 gene is an important player in the immune response. A mutation in the CCR5 gene, called the Delta32 mutation, significantly reduces the chance of an HIV infection.
Lymphedema can be caused by various factors such as a traumatic injury, genetics, or even cancer. Discover how your genetics influence the risk of developing the condition.
Mannose-binding lectin, also known as mannose-binding protein, is involved in the body’s innate defense against infections. Find out how genetic variants in this system increase your susceptibility to specific pathogens.
The World Health Organization (WHO) categorizes light at night as a probable carcinogen. Learn why dim light at night increases your risk of breast cancer — and what you can do to easily reduce this risk. (Member’s article)
Emulsifiers, found in many processed and packaged foods, can trigger an inflammatory response in the intestines based on whether you carry specific genetic variants.
Genetic variants significantly influence individual salt sensitivity, with certain genotypes making people more prone to high blood pressure in response to high salt intake
An easy way to improve sleep and increase melatonin production at night is to wear blue light blocking glasses before bed. Explore the research on why this is so important, and learn about the different options available for blue-blocking glasses.
Tyramine intolerance happens when you can’t break it down. Too much tyramine can lead to a hypertensive crisis. Learn more and check your genetic raw data for results.
Low levels of BDNF (Brain-derived neurotrophic factor) are linked to introversion, stress resilience, cognition, and depression levels. Discover ways to increase your BDNF levels and mitigate the problems associated with the BDNF gene variants. (Member’s article)
Exposure to certain kinds of mold can cause chronic, negative health effects. Discover how genetic variants impact the ability to handle mycotoxins.
Tetrahydrobiopterin (BH4) is an essential cofactor in the production of neurotransmitters and nitric oxide. Genetic variants impact BH4 levels which can affect heart disease, cognitive function, and immune response.
Skin cancer is the most common form of cancer and many forms are highly treatable if caught early. Learn more about the different types of skin cancer, your genetic risks, and lifestyle changes to help reduce risk.
Genetics plays a role in the likelihood of having chronic sinus problems. This article looks at the genetic reasons driving some people to have chronic sinus infections.
Ferritin is the storage protein for iron in the body. Storing too little or too much iron can be an indicator of an underlying problem. Discover the genetic variants that impact ferritin and how to increase ferritin with supplements or foods.