NLRP3: Genetics Variants that Increase Chronic Inflammation
What makes people more susceptible to chronic inflammatory diseases? The root of the over-activation of inflammation for some people could be the NLRP3 inflammasome.
What makes people more susceptible to chronic inflammatory diseases? The root of the over-activation of inflammation for some people could be the NLRP3 inflammasome.
Tetrahydrobiopterin (BH4) is an essential cofactor in the production of neurotransmitters and nitric oxide. Genetic variants impact BH4 levels which can affect heart disease, cognitive function, and immune response.
The APOE gene variants are linked with the risk of Alzheimer’s disease. Find out whether you carry the APOE risk type for Alzheimer’s – and learn what research shows about supplements and lifestyle changes to prevent this disease.
Plasmalogen levels in the brain are key to brain health. Low plasmalogen is linked to Alzheimer’s and ME/CFS. Healthy ways to boost your levels.
Explore the research about how nicotinamide riboside (NR) and NMN are being used to reverse aging. Learn about how your genes naturally affect your NAD+ levels and how this interacts with the aging process.
Lion’s mane mushrooms have a long history of being used as a medicinal food for increasing energy, improving nerve function, and boosting brain power.
The Klotho protein is involved in many of the diseases of aging. Learn more about this gene and find out how your Klotho variants may impact healthy aging.
Two natural fibrinolytics to reduce clotting are nattokinase and lumbrokinase. Learn more about these options based upon the newest research and clinical trials.
Discover the role of TNF-alpha in inflammation and its link to chronic diseases. Learn how genetic variants affect TNF-alpha levels and explore natural solutions for chronic inflammation.
Genetic variants of the BChE gene decrease its enzyme’s activity. This can lead to various and seemingly unconnected consequences…such as an increased risk for Parkinson’s or food sensitivity to potatoes.
New research suggests the benefits of luteolin (a flavonoid found in fruits, vegetables, and herbs) may include anti-inflammatory and neuroprotective properties.
Prions are able to infect, causing the normal protein around them to also misfold. These misfolded proteins aggregate to cause neurogenerative disease. Susceptibility to prion diseases depends in part on your genes.
GLP-1, a small peptide, tells your pancreas to release insulin after a meal and signals to your brain to stop eating. If you are someone who struggles with appetite, weight, or with diabetes, the GLP-1 hormone may be at the heart of your issues.
Several genes have been identified as longevity genes, linked to an increase in lifespan. Most importantly, these particular genetic variants show links to a longer ‘healthspan’. Check your genetic data to see if you carry the FOXO3A and IGF1R variants associated with healthy longevity.
Learn how new research on brain aging and dementia connects the serotonin 2A receptor with psychedelics, brain aging, and Alzheimer’s.
Just like there are genetic variants that increase the risk of Alzheimer’s, there are also variants that protect against this disease. Check your genetic data to get a better picture of your risk factors. (Member’s article)
Melatonin is important for setting your circadian rhythm and for immune health. Dig into the details on melatonin supplements, scientific research, and more.
The TREM2 gene is important in how the brain’s immune system functions. Learn how variants in this gene impact the risk for Alzheimer’s disease.
Our body has built-in antioxidants that fight against cellular stress. The superoxide dismutase enzyme fights against oxidative stress in your cells.
Studies show that lithium in ground water is linked to lower levels of Alzheimers, depression, and aggression. Find out how lithium may be important in Alzheimer’s prevention.
More than just a sleep hormone, melatonin is at the heart of many health topics. Your genetic variants play a big role in the production of melatonin. Learn how your lifestyle and diet interact with your melatonin-related genes.
One cause of many of the diseases of aging is the buildup of advanced glycation end products (AGEs). Your genes interact with your diet – and cooking methods – in the build-up of AGEs. Learn whether this is something that is important for you to focus on. (Member’s article)
Key takeaways: ~ Alzheimer’s disease is a real risk for many people as they age. It is the most common form of dementia, affecting almost 1 in 3 people by the end of life. ~ One big change we have all been subjected to is the explosion of electronics and … Read more
Low levels of BDNF (Brain-derived neurotrophic factor) are linked to introversion, stress resilience, cognition, and depression levels. Discover ways to increase your BDNF levels and mitigate the problems associated with the BDNF gene variants. (Member’s article)
Too much blue light at night is standing out as a player in circadian rhythm dysfunction and can increase your risk of Alzheimer’s disease. Discover ways to improve your sleep quality and environment to help lower your modifiable risk.