PCOS: Causes, Genetics, and Natural Solutions
Explore the complexities of PCOS, including symptoms, hormonal dysregulation, and the role of genetics. Learn how to target individual pathways.
circadian rhythm
MC4R: Leptin, Melanin, Genes and Weight Gain
There are several key players in our body’s regulation of hunger, satiety, and energy expenditure. Leptin and ghrelin are two pivotal hormones involved in our desire to eat. Within that leptin pathway, another key regulator of our body weight is MC4R. (Member’s article)
DEC2 Gene: Short Sleep Mutation
Are you naturally a short sleeper? Mutations in the DEC2 gene decrease the need for sleep.
ME/CFS: Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (and Long Covid?) Genes
Take a look into the science of the lingering effects of viruses, including chronic fatigue syndrome and long-haul viruses.
Genetic Mutations that Protect Against Alzheimer’s Disease
Just like there are genetic variants that increase the risk of Alzheimer’s, there are also variants that protect against this disease. Check your genetic data to get a better picture of your risk factors. (Member’s article)
Supplemental Melatonin: Immune Response and Inflammation
Melatonin is important for setting your circadian rhythm and for immune health. Dig into the details on melatonin supplements, scientific research, and more.
Ghrelin: The Hunger Hormone
The hunger hormone, ghrelin, is important in appetite regulation and satiety. Learn how your genes interact with your diet when it comes to ghrelin levels. (Member’s article)
Circadian rhythm disruption as a root cause of depression
For some people, circadian disruption can be chronic – and at the heart of depression or mood disorders. Genetic variants play a role in this susceptibility. Fortunately, there are solutions that may help.
Melatonin: Key to Health and Longevity
More than just a sleep hormone, melatonin is at the heart of many health topics. Your genetic variants play a big role in the production of melatonin. Learn how your lifestyle and diet interact with your melatonin-related genes.
PPAR-Delta: Burning off the Fat
PPARδ is a key player in how and when your muscles burn fat for fuel. Genetic variants in the PPARD gene impact how well your muscles utilize fatty acids. These variants also impact how much of a fat-burning benefit you get from exercise.
Carbohydrate metabolism: Genetics, Insulin, and Carbs
Genetic variations play a role in how people react to carbohydrates in the diet. Learn about a few genes that affect insulin or glucose levels based on carbohydrate consumption. Use your genetic raw data and discover how your body handles carbohydrates.
9 Genes that Impact the Response to Vaccines
Genetics plays a huge role in how an individual responds to a vaccine. Learn more about vaccines, immunity, and genetic variants that affect the response.
Problems sleeping? Your genes can point to individualized solutions
An overview explaining how your genes impact sleep, including insomnia, restless leg, narcolepsy, and circadian rhythm genes. Start here and then dive deeper into the specific topics.
Circadian Rhythm and Your Immune Response to Viruses
Your circadian rhythm influences your immune response. Learn how this rhythm controls white blood cell production and why melatonin protects against viral and bacterial infections.
Genetics and Seasonal Affective Disorder
Seasonal Affective Disorder (SAD) is characterized by recurrent depression with a change in the season usually in fall/winter for most. Scientists think this is possibly due to an aberrant response to light – either not enough brightness to the sunlight or not enough hours of light. Your genes play a big role in this responsiveness to light.
Vitamin D Genes
Your vitamin D levels are impacted by sun exposure and your genes. Learn more about how vitamin D is made in the body and how your genetic variants impact your levels.
Bipolar Disorder, Depression, and Circadian Clock Genes
New research shows that depression and bipolar disorder are linked to changes or disruption in circadian genes. Some people carry genetic variants in the circadian genes that make them more susceptible to circadian disruption.
BMAL1: Core circadian gene with links to heart disease, cancer, and diabetes
A core circadian rhythm gene, BMAL1, influences heart disease risk, diabetes, and cancer. Check your genes and learn how to mitigate the risk.
Resilience: Genetic Variants Involved in Surviving Childhood Trauma
Exposure to childhood trauma, such as exposure to abuse, violence, or repeated stress, can have a long-lasting effect. Genetic differences in the CRHR1 gene are linked to elevated cortisol levels in adults who were exposed to trauma in childhood.
Alzheimer’s Disease
Key takeaways: ~ Alzheimer’s disease is a real risk for many people as they age. It is the most common form of dementia, affecting almost 1 in 3 people by the end of life. ~ One big change we have all been subjected to is the explosion of electronics and … Read more
Leveraging your gut microbiome to change your gene expression
Learn how your gut microbiome influences the expression of your core circadian rhythm genes.
Why Light at Night Increases Cancer Risk
The World Health Organization (WHO) categorizes light at night as a probable carcinogen. Learn why dim light at night increases your risk of breast cancer — and what you can do to easily reduce this risk. (Member’s article)
Circadian Rhythm Genes: Mood Disorders
Circadian rhythm disruption can drive mood disorders. Learn more about the genes involved and the ways to normalize your circadian rhythm.
Alzheimer’s and Light at Night: Taking action to prevent this disease
Too much blue light at night is standing out as a player in circadian rhythm dysfunction and can increase your risk of Alzheimer’s disease. Discover ways to improve your sleep quality and environment to help lower your modifiable risk.
Circadian Rhythm Genes: Our Internal Clocks
The body’s circadian clock regulates many different functions over the course of a 24-hour day. The genes that code for different parts of the circadian clock have a wide-ranging effect on sleep, mood, and overall health.