Chronic Inflammation: Causes and Natural Solutions
Take a deep dive into the causes of chronic inflammation and learn how to target specific inflammatory pathways to reverse or prevent chronic disease.
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Nrf2 Pathway: Increasing the Body’s Ability to Get Rid of Toxins
The Nrf2 (Nuclear factor erythroid 2–related factor) signaling pathway regulates the expression of antioxidants and phase II detoxification enzymes. It is a fundamental pathway important in how well your body functions. Your genetic variants in the NFE2L2 gene impact this NRF2 pathway.
COMT: How to Optimize Your Supplements for Your COMT Genotype
Some supplements interact with COMT variants to impact the rate at which neurotransmitters are broken down. Check your COMT genotype and discover how this may affect your reaction to different supplements or combinations of supplements.
Are Cold Sores Genetic? Who gets them and why
While many people carry the HSV virus, only about 30% will get cold sores. Genetics is one reason.
MS Genes: Decoding the Genetic Factors Behind Multiple Sclerosis
MS susceptibility is linked to both genetic causes and environmental factors. Learn how those two combine – and possible solutions.
Beating Flu Season
Are you more genetically susceptible to the flu? Learn how your genes play a role and discover research-backed natural options to beat the flu.
GLP-1: Genetic Variants Related to GLP1 Weight Loss Drugs
GLP-1 receptor agonists are used for weight loss by increasing the body’s sensitivity to insulin and reducing hunger. However, genetic variants can alter the response in some people.
Prostate Problems: Genetic reasons and research on solutions
Do you know someone that suffers from prostate problems? Learn more about this important gland and how your genes affect your risk.
TTR gene: amyloidosis, cardiomyopathy, hATTR CM
New research shows that hereditary transthyretin amyloidosis (hATTR) may be more common, especially in people of African ancestry. Understand your genetic risk before irreversible damage.
Tendinitis Genes
Do you have problems with your tennis elbow, rotator cuff, knees, or Achilles tendon? Discover how your genes influence the risk of having tendon problems.
Mercury Detoxification: Genomics and Solutions
What are the physiological effects of mercury and how does the body eliminates it? Discover how genetic variants play a role in how quickly you excrete mercury.
Genetic Causes of Male Infertility
Almost 10% of couples worldwide struggle with infertility. Learn more about your genetic susceptibility and dig deeper into the lifestyle factors that could affect your sperm.
Are you genetically less likely to get the flu?
Have you ever wondered why some people never seem to get the flu when it is going around? Simply put, some people are just more susceptible to getting the flu than others. Learn more and see if you are more or less susceptible to the flu.
NQO1 Gene: Metabolism of Quinones, Benzene, and More
The NQO1 gene codes for an important enzyme in phase II detoxification. This enzyme is responsible for metabolizing the cancer-causing benzene (e.g. from air pollution) and cigarette toxins. Learn more and check your genes. (Member’s article)
Heat Shock Proteins: Cellular Resilience
Heat shock proteins are activated by cells in response to a stressful condition, such as exposure to high heat. Learn more about the essentials of heat shock proteins, including how to activate them and the genetic variants that impact how well they work.
GLP-1: Appetite, Insulin, and Genetics
GLP-1, a small peptide, tells your pancreas to release insulin after a meal and signals to your brain to stop eating. If you are someone who struggles with appetite, weight, or with diabetes, the GLP-1 hormone may be at the heart of your issues.
Longevity Genes: Hacking healthspan using genomics
Several genes have been identified as longevity genes, linked to an increase in lifespan. Most importantly, these particular genetic variants show links to a longer ‘healthspan’. Check your genetic data to see if you carry the FOXO3A and IGF1R variants associated with healthy longevity.
FTO and m6A methylation: From COVID to Cancer to Obesity
The initial research on the FTO gene was all about how it relates to increased BMI and increased fat cell creation. More recently, researchers discovered that FTO is an m6A eraser that removes methyl groups from mRNA. This discovery has opened up huge avenues of research on topics from cancer to immune response to heart disease.
NLRP3 Inflammasome, Genetics, and Chronic Inflammation
What makes people more susceptible to chronic inflammatory diseases? The root of the over-activation of inflammation for some people could be the NLRP3 inflammasome.
Rapamycin, mTOR, and Your Genes
Rapamycin is an antibiotic used as an immunosuppressant, an anti-cancer agent, and to prevent blocked arteries. Rapamycin is now the focus of longevity and healthspan-extending research by inhibiting mTOR.
SCD1: A lynchpin of metabolism
The SCD1 enzyme converts saturated fatty acids to unsaturated fats. Learn how your genes impact this enzyme, and how this relates to weight loss.
Skin Cancer: Genetics and Prevention
Skin cancer is the most common form of cancer and many forms are highly treatable if caught early. Learn more about the different types of skin cancer, your genetic risks, and lifestyle changes to help reduce risk.
Building Up Iron: Hemochromatosis mutations
A couple of common mutations can cause you to build up iron, leading to iron overload or hemochromatosis. It is one genetic disease where knowledge is really powerful – you can completely prevent hemochromatosis through blood donations.
Fibroids: Genes, root causes, and solutions
Uterine fibroids are a problem for a lot of women, especially after age 30. Fibroids are benign tumors that grow in the muscle cells of the uterus. This article will dig into the causes of fibroids, explain how your genetic variants can add to the susceptibility, and offer solutions that are backed by research. (Member’s article)
Will statins give you muscle pain?
Statins are one of the most prescribed medications in the world. One side effect of statins is myopathy, or muscle pain and weakness. Your genetic variants are significant in whether you are likely to have side effects from statins.