Do you know of someone with unexplained heart palpitations, spiking blood pressure, dizziness, and tinnitus? Discover how research is linking these symptoms to histamine, mast cells, and the spike protein.
High Lp(a) levels are a big risk factor for sudden heart attacks. Your Lp(a) levels are mainly controlled by your genetic variants. Check to see if you carry genetic variants that increase or decrease Lp(a).
von Willebrand disease is a bleeding disorder in which blood doesn’t clot properly. Discover how genetic mutations cause the von Willebrand factor not to perform as it should.
Coronary artery disease (CAD) is heritable. Understanding your genes and a ‘heart healthy’ lifestyle can prevent heart attacks and death.
Your genes combine with your diet to influence your LDL cholesterol level. Learn more about why LDL cholesterol levels may matter in heart disease and find out how your genes are important here.
The initial research on the FTO gene was all about how it relates to increased BMI and increased fat cell creation. More recently, researchers discovered that FTO is an m6A eraser that removes methyl groups from mRNA. This discovery has opened up huge avenues of research on topics from cancer to immune response to heart disease.
Fibrinogen is a protein that is essential for creating blood clots when you get a wound. But higher levels of fibrinogen are a major risk factor for heart disease and DVT. Learn how your genes impact your fibrinogen level.
What makes people more susceptible to chronic inflammatory diseases? The root of the over-activation of inflammation for some people could be the NLRP3 inflammasome.
Rapamycin is an antibiotic used as an immunosuppressant, an anti-cancer agent, and to prevent blocked arteries. Rapamycin is now the focus of longevity and healthspan-extending research by inhibiting mTOR.
Mast cells are essential to your innate immune system, defending against pathogens and allergens. For some people, mast cells can be triggered too easily, giving allergy-like responses to lots of different substances.
Do you end up getting sore after pretty much every workout at the gym? It could be that a deficiency caused by the AMPD1 genetic variant is the cause.
While large population studies show the benefits of aspirin, research shows that these heart-health benefits are dependent on your genes. Find out more and check your genetic raw data.
There are several important variants in the PCSK9 gene. Some variants cause lower LDL-cholesterol and decrease the risk of heart disease by 2-fold. Other variants increase LDL-c and increase the risk of heart disease.
In a nutshell, the anti-inflammatory flavonoid found in citrus called hesperidin may help with cardiovascular health and preventing neuroinflammation. Learn more about this flavonoid found in citrus fruits.
Hypertension risk can be modifiable in terms of diet and exercise however genetics can play a part in risk. Learn more about how the CYP11B2 variant can increase the risk of hypertension.
High triglycerides are linked with an increased risk of cardiovascular disease. Both genetics and diet combine to elevate triglyceride levels. Learn how your genes interact with what you eat to lower your triglycerides.
A couple of common mutations can cause you to build up iron, leading to iron overload or hemochromatosis. It is one genetic disease where knowledge is really powerful – you can completely prevent hemochromatosis through blood donations.
A core circadian rhythm gene, BMAL1, influences heart disease risk, diabetes, and cancer. Check your genes and learn how to mitigate the risk.
Your telomeres are the region at the end of each chromosome that keeps your DNA intact when your cells divide. Genetics plays a role here – along with diet and lifestyle.
There has been a decades-long debate about which type of fat is best: saturated fat vs polyunsaturated fat. It may depend on your genes as to which answer is right for you. Learn more about this debate and find out how your genes play a part.
The PIA2 variant of the ITGB3 gene is linked to an increased risk of blood clots including stroke, heart attack, and DVT. But this variant also comes with a positive trade-off. Learn more with your genetic raw data.
Chronic inflammation is the driver of many common diseases such as heart attacks, diabetes, obesity, and autoimmune diseases. C-Reactive Protein is a marker of inflammation. Genetic variants can increase or decrease CRP levels.
Wondering how your genes influence your reaction to coffee? Find out if you will benefit from drinking coffee and how this interacts with your genes. (Member’s article)
Vitamin E, an antioxidant, is often promoted to prevent cardiovascular disease and LDL cholesterol oxidation. New research shows a genetic component to whether a person benefits from supplementation. Find out more by checking your genetic data.