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HPA Axis disfunction, ways to reduce cortisol levels, genetic variants related to HPA Axis disfunction.

HPA Axis Dysfunction: Understanding Cortisol and Genetic Interactions

Cortisol is a hormone produced by the adrenal glands in times of stress, and it also plays many roles in your normal bodily functions. It is a multi-purpose hormone that needs to be in the right amount (not too high, not too low) and at the right time. Your genes play a big role in how likely you are to have problems with cortisol.

MTHFR mutations explained, frequency of C677T SNP, A1298C SNP, Supplement Interaction, MTHFR variant risks

MTHFR Mutation: What is it? How to check your raw data.

The MTHFR gene is important for how your body utilizes folate (vitamin B9) for creating neurotransmitters, detoxifying toxicants, and maintaining a healthy heart. Check your 23andMe or AncestryDNA data for the MTHFR C677T and A1298C variants.

Nicotinamide riboside and NMN - Boosting NAD+ in aging

Nicotinamide Riboside and NMN: Boosting NAD+ in Aging

Explore the research about how nicotinamide riboside (NR) and NMN are being used to reverse aging. Learn about how your genes naturally affect your NAD+ levels and how this interacts with the aging process.

Folate Optimization: MTHFR and Fertility

MTHFR variants affect the conversion of folate into the active form. Learn how this can affect you if you are trying to get pregnant.

picture of natural supplements with a dollar sign

Guide: Saving Money on Supplements

Five quick examples of how you could use your genetic data to dial in the supplements worth trying and which ones to skip for now.

Genetic Causes of Male Infertility

Almost 10% of couples worldwide struggle with infertility. Learn more about your genetic susceptibility and dig deeper into the lifestyle factors that could affect your sperm.

Cystic Fibrosis: Check to see if you are a carrier

Being a carrier of a cystic fibrosis mutation increases the risk of several diseases including pneumonia from respiratory viruses, pancreatitis, and male infertility. (Member’s article)

Melatonin: Key to Health and Longevity

More than just a sleep hormone, melatonin is at the heart of many health topics. Your genetic variants play a big role in the production of melatonin. Learn how your lifestyle and diet interact with your melatonin-related genes.

Dads matter: MTHFR variants in fathers affect miscarriage risk

Dads matter – in conception, pregnancy, and throughout life. It is easy to see how prospective moms need to clean up their diets, exercise, and sleep well before getting pregnant, but recent studies show that a dad’s MTHFR variants also affect infertility and miscarriage risk.

Twins: Genetic SNPs that Increase the Odds of Having Twins

Twins tend to ‘run in families’, which is a colloquial way of saying that there is a hereditary component that increases the likelihood of having twins. Check your genetic data (women only :-) to see if you are more likely to have twins.