Parkinson’s Disease Risk: Genetics, Environmental Exposures, and Prevention Strategies
Parkinson’s: Explore key genes, environmental risks, gut microbiome factors, and research‑based lifehacks that may help protect dopaminergic neurons.
nicotine
Trimethylaminuria: FMO3 mutations that cause malodorous body odor
Often referred to as ‘fish odor disease’, trimethylaminuria causes a strong odor in sweat, urine, and breath. This article explores the FMO3 gene, which encodes the enzyme that breaks down trimethylamine.
HMGB1 gene: inflammatory response protein important in sepsis and COVID-19
The HMGB1 protein has a unique role in activating the inflammatory response pathways. Increased HMGB1 levels will call up the troops for a big response to an infection. Discover how genetic variants of this protein vary the risk of cancer, inflammation, and sepsis to name a few.
CYP2A6: Breaking down nicotine and other medications
How many cigarettes a day a person smokes – and how hard it is for them to quit – is at least partly dependent on the CYP2A6 gene. This enzyme also metabolizes several important cancer drugs.