Join Here   |   Log In

Vitamins & Nutrients: Exploring Nutrigenomics

Your genes influence how well your cells absorb, transport, and utilize nutrients. We are all genetically different, and your genes give you unique dietary needs and strengths. Genetic data can give you a starting point to know where you may need more – or less – of a specific nutrient. It can also point to problems with specific foods, like dairy, or with a component of foods, like histamine or tyramine.

Here you will find the tools you need to dial in your nutrition. This isn’t a one-size-fits-all approach! No protocols here… Instead, you’ll learn which nutrients are likely important for you, and then pick from possible solutions in the Lifehacks section.

Members: Check out your Vitamins & Nutrients Summary Report

Latest articles:

Casein and Cow’s Milk Allergies

Casein and Cow’s Milk Allergies

Cow’s milk allergy can be due to your immune system responding to casein or β-lactoglobulin. Genetic variants in immune-system genes increase susceptibility – along with environmental factors.
Vitamin K genetic variants, vitamin k and bone health

Vitamin K: Bone Strength, Blood Clots, Calcification, and Genetics

Genetic variations cause people to have higher or lower levels of vitamin K, which can affect blood clotting. Learn more about the genes that affect vitamin K and how it relates to your genetic raw data.

Vitamins & Micronutrients

Vitamins and micronutrients interact with genetic variants related to their absorption, transport into cells, conversion into their active form, and

Vitamin K genetic variants, vitamin k and bone health

Vitamin K: Bone Strength, Blood Clots, Calcification, and Genetics

Genetic variations cause people to have higher or lower levels of vitamin K, which can affect blood clotting. Learn more about the genes that affect vitamin K and how it relates to your genetic raw data.
Vitamin B6 deficiency genes, foods high in vitamin B6

Vitamin B6: Genetics, Absorption, and Deficiency

Vitamin B6 is an important co-factor in hundreds of different enzymatic reactions. Low levels of B6 are linked to an increased risk of diabetes, cardiovascular disease, neurodegenerative diseases, and cancer. B6 is also essential for reducing oxidative stress and inflammation.
Manganese deficiency, manganese transport, genes that affect manganese levels

Manganese: Genetic Interactions, Diet, and Supplements

Manganese is an essential mineral needed in the right amount. It is important for health as an antioxidant cofactor, but too much is neurotoxic.
Types of Choline, Choline Genes, Foods high in Choline

Which Type of Choline Works Best with Your Genes?

Choline is an often neglected nutrient essential to a healthy diet. Your genes are important in how much and which types of choline you need.
MTHFR mutations explained, frequency of C677T SNP, A1298C SNP, Supplement Interaction, MTHFR variant risks

MTHFR Mutation: What is it? How to check your raw data.

The MTHFR gene is important for how your body utilizes folate (vitamin B9) for creating neurotransmitters, detoxifying toxicants, and maintaining a healthy heart. Check your 23andMe or AncestryDNA data for the MTHFR C677T and A1298C variants.
MTR and MTRR genetic variants, Vitamin b12 genetic variants, choosing the right form of B12 for your genetic variants

MTR and MTRR Genes: Vitamin B12, Homocysteine, and Methylation

There are several genes that can influence your absorption, transport, and need for vitamin B12. Some people need higher amounts of B12, and some people thrive on different forms of B12. Take a look at your genetic data to see if you should up your intake of B12.
Wilson's Disease, ATP7B Gene mutations, role of zinc balancing heavy metals

Wilson’s disease: ATP7B Gene Mutations and Copper Accumulation in the Brain

Mutations in ATP7B can cause copper dysregulation and Wilson’s disease. People carrying one copy of the mutation may also have subtle changes.
Genes That Impact Magnesium Deficiency, magnesium transport and magnesium reuptake, foods high in magnesium

Magnesium Deficiency? Genes that Impact Magnesium Levels

Are your magnesium levels low? Understanding your genes can help you decide whether you may need more magnesium in your diet or via supplements.
Vitamin C: Nutrigenomics, Transport, and Genetic Deficiency, Vitamin C transport genes SLC23A1, SLC23A2. Food sources of vitamin C

Vitamin C: Nutrigenomics, Transport, and Genetic Deficiency

Like most nutrients, our genes affect how vitamin C is absorbed, transported, and used by the body. It can influence your risk for certain diseases and make a difference in the minimum amount of vitamin C you need to consume each day.
Thiamine Genetics, foods high in thiamine, thiamine transporters

Thiamine: Genomics, Cellular Energy, and Cognitive Function

Also known as vitamin B1, thiamine is essential for energy production and brain function. Learn how your genes influence your need for thiamine.
Nutrigenomics and the SNPs related to zinc, inflammation, and diabetes

Zinc genes: The healing power of zinc

Learn why zinc is important for your immune system and so much more. Find out how your genes impact your need for zinc and discover ways of boosting your zinc status. 
Selenium and Your Genes

Selenium and Your Genes

Selenium is a trace element found in certain foods. Learn how selenium is used in the body, why it is important, and how genetic variants can make someone more susceptible to problems with a selenium-deficient diet.
Genetics and Vitamin D Levels

Vitamin D Genes

Your vitamin D levels are impacted by sun exposure and your genes. Learn more about how vitamin D is made in the body and how your genetic variants impact your levels.
Choline, An Essential Nutrient Impacted By Genes, PEMT Gene variants and CHKA Gene, Cholinergic Anti-Inflammatory Pathway

Choline, An Essential Nutrient Impacted By Genes

An essential nutrient, your need for choline from foods is greatly influenced by your genes. Find out whether you should be adding more choline into your diet.
Vitamin E, Genetics, and Inflammation

Vitamin E, Genetics, and Inflammation

Vitamin E, an antioxidant, is often promoted to prevent cardiovascular disease and LDL cholesterol oxidation. New research shows a genetic component to whether a person benefits from supplementation. Find out more by checking your genetic data.

Food Intolerances & Allergies

Food intolerances can be due to genetic variants that decrease specific enzymes needed to break down a food , such as lactase. Allergies are generally an interaction between genetic susceptibility and environmental factors.

Casein and Cow’s Milk Allergies

Casein and Cow’s Milk Allergies

Cow’s milk allergy can be due to your immune system responding to casein or β-lactoglobulin. Genetic variants in immune-system genes increase susceptibility – along with environmental factors.
Histamine intolerance symptoms, genetic components, histamine

Histamine Intolerance: Genetic Report, Supplements, and Real Solutions

Genetics plays a big role in how well your body breaks down histamine. You can use your genetic data to figure out if your genes are part of the reason why you have histamine intolerance.
Fructose Intolerance: ALDOB Gene, symptoms of fructose intolerance, Foods High in Fructose

Fructose Intolerance: Hereditary or Dietary?

Fructose intolerance can be due to a rare mutation in the ALDOB gene or it can be due to reduced intestinal absorption.
Nickel allergy genetics, foods to avoid with nickel allergies

Nickel Allergy: Genetics, causes, natural solutions

Nickel allergy can cause sensitivity to foods that contain nickel. Learn about how genes increase susceptibility and solutions.
LCT Gene and lactose intolerance, lactose intolerance by population group, find in 23andMe, AncestryDNA data

Lactose Intolerance: How to Check Your Genetic Data

Your genes control whether you are likely to produce lactase as an adult. Check your 23andMe or other genetic data to see if you are likely to enjoy a big glass of milk.
Tyramine Intolerance: Metabolism of Tyramine, MAOA, FMO3, and CYP2D6 enzymes, foods high in tyramine

Tyramine Intolerance: Metabolism of Tyramine

Tyramine intolerance happens when you can’t break it down. Too much tyramine can lead to a hypertensive crisis. Learn more and check your genetic raw data for results.
Mushroom Intolerance: IBD, Ergothioneine and the OCTN1 Gene

Mushroom Intolerance: Ergothioneine and the OCTN1 Gene

Mushrooms contain a healthy antioxidant called ergothioneine. But for people with a SLC22A4 genetic variant, this antioxidant can be too much of a good thing, leading to intestinal problems. Check your genetic data to see if you carry this mushroom intolerance variant.

Dietary Sensitivities

Dietary sensitivities include foods that you may want to be careful with due to a genetic connection to an increased risk, such as for oxalate metabolism and kidney stones.

Genetic SNPs that impact oxalates

Oxalates, Kidney Stones, & Joint Pain: Genetic Reasons to Avoid Oxalates

Green smoothies have been a health fad for quite a while now, but these health drinks can be a double-edged sword for some people due to their high oxalate content. Find out if you are genetically prone to kidney stones and what to do about it.
Butyrylcholinesterase (BChE) gene variants

BChE gene: Nightshade sensitivity, Anesthesia risk

Genetic variants of the BChE gene decrease its enzyme’s activity. This can lead to various and seemingly unconnected consequences…such as an increased risk for Parkinson’s or food sensitivity to potatoes.
FASD1 and FASD2 genes, converting Omega 3&6 in DHA and EPA

FADS1 and FADS2: Omega-3 and Omega-6 Fatty Acids

We all vary in how well we convert the plant-based omega-3 oils into the DHA and EPA that our body needs. Some people are really poor at this conversion and thus should either eat more fish or consider taking a DHA / EPA supplement. Learn more about how your variants might affect your health.
TRPV1 Gene: Spicy Foods, Cold, and CBD Oil

TRPV1 gene: Spicy foods, cold, and CBD oil

The TRPV1 receptor is activated by capsaicin in spicy foods. But there is a lot more to this story… find out how this receptor impacts diabetes, metabolic function, and more.
Short-chain Acyl-CoA Dehydrogenase Deficiency

Short-chain Acyl-CoA Dehydrogenase Deficiency

If you have tried fasting or perhaps a ketogenic diet and felt horrible, there could be a genetic reason. You might carry a genetic mutation that causes SCADD (short-chain acyl-CoA dehydrogenase deficiency).
Caffeine sensitivity genetics, CYP1A2, ADORA2A

Caffeine Sensitivity and Your Genes

Caffeine remains the most popular ‘drug’ of choice for a large percentage of the population. Genetics determines how quickly your body processes and eliminates caffeine and whether it is likely to make you jittery or anxious.

Carbohydrate Metabolism

Genetic variants can influence how you break down and utilize carbohydrates.

Carbohydrate metabolism: Genetics, Insulin, and Carbs

Carbohydrate metabolism: Genetics, Insulin, and Carbs

Genetic variations play a role in how people react to carbohydrates in the diet. Learn about a few genes that affect insulin or glucose levels based on carbohydrate consumption. Use your genetic raw data and discover how your body handles carbohydrates.
Hunter-Gatherer or the Farmer Genetic Variant, Glucose transport

Do you carry the Hunter-Gatherer or the Farmer Genetic Variant

Our ancient ancestors lived much differently than we do today. They were hunter-gatherers, living off of fish, meat, and plant foods that they gathered. A huge shift took place when those hunter-gatherers began farming, growing grains, and storing them so that there would be food available all year. Learn if you carry the hunter-gatherer or farmer gene variant. (Member’s article)
Digesting Carbohydrates: Amylase (AMY1 Gene)

Digesting Carbohydrates: Amylase variants

Carbohydrate digestion begins in the mouth with an enzyme called amylase. Take a look into how the amylase enzyme works, genetic variants that impact your production of amylase, and solutions if you are low in amylase.

Glucose Response: Caffeine + Sugar + Genes

Consuming caffeine along with carbohydrates changes glucose response for people with certain genetic variants and yet it doesn’t change blood glucose levels for those without the variants. Find out more about your response. (Member’s article)

Personalized Nutrition

These articles bring together practical ways to implement personalization for your diet.

Alcohol and Histamine intolerance, DAO enzyme, symptoms of histamine intolerance

Alcohol & Histamine Intolerance: Understanding the Connection

Drinking alcohol is often a problem for people with histamine intolerance. Learn about the pathways that are involved and how to avoid alcohol-induced reactions.
SCD1: Saturated Fatty Acid Conversion

SCD1: A lynchpin of metabolism

The SCD1 enzyme converts saturated fatty acids to unsaturated fats. Learn how your genes impact this enzyme, and how this relates to weight loss.
Foods rich in vitamin A in its retinol form

Foods rich in vitamin A – retinol form

Interested in vitamin A foods? This article focuses on foods high in the retinol form of vitamin A that your body doesn’t need to convert plus some great links to vitamin A-rich recipes.

Folate-rich recipes for MTHFR

Getting enough folate in your diet? We’ve collected some simple nutritional tools and recipes to get you on track.
Saturated Fats, ACE Gene, APOE gene and saturated fats

Saturated Fat and Your Genes (ACE gene)

There has been a decades-long debate about which type of fat is best: saturated fat vs polyunsaturated fat. It may depend on your genes as to which answer is right for you. Learn more about this debate and find out how your genes play a part.

Is intermittent fasting right for you?

Intermittent fasting and ketosis have a lot of benefits, but they may not be right for you. Your genes play a role in how you feel when fasting.

Nutrigenomics: Use your 23 and Me data

A list of focused articles on nutrigenomics looking into background science, research studies, and related genetic variants.
5 Ways to Optimize Your Diet, Based on Your Genes

5 ways to optimize your diet, based on your genes

What is right for your body? Discover the 5 quick ways to optimize your diet based on your genes.
Coffee: Benefits Based on Your Genes

Coffee: Benefits based on your genes

Wondering how your genes influence your reaction to coffee? Find out if you will benefit from drinking coffee and how this interacts with your genes. (Member’s article)